C# Complete Best of 7 C# books in one. I reach for this before looking to Google or MSDN.
jQuery in Action Fantastic cross-browser Javascript library. I use it often.
JavaScript Pocket Reference (2nd Edition) Because we all need a hint now and then.
The Essential Guide to Open Source Flash Development Why spend hundreds on developing Flash? This book + FlashDevelop = inexpensive education on high-price skills.
Lucene in Action (In Action series) Very powerful embeddable indexing engine. I use it as part of Solr.
PostgreSQL (2nd Edition) This has been a huge boon to my database management skills.
ASP in a Nutshell, 2nd Edition Great object reference for those still using legacy ASP. I still have mine.
PHP and MySQL Web Development (4th Edition) I bought two good references at once when I picked this up.